Recent research by the University at Buffalo School of Dental Medicine has shown an antidepressant link to dental implant failure. The recent findings back up a report in 2014 by McGill University researchers who reported finding a link between Selective Serotonin Reuptake Inhibitors (SSRI) antidepressants and a doubling of the risk of dental implant failure.
Implant failure amongst antidepressant users were about four times higher compared with controls in the study. The higher rate of failure is linked to how antidepressants affect bone metabolism/growth and heighten the risk of dry mouth (clinically known as xerostomia). These side effects contribute to the failure of dental implants as the mouth fails to heal properly. The researchers also that each year of antidepressant use doubled the odds of failure.
Additional side effects of antidepressants include osteoporosis, akathisia (a disorder with the symptoms of needing to be in constant motion), and teeth grinding. All of these can contribute to dental implant failure.
Researcher Sebastiano Andreana, Associate Professor and Director of Implant Dentisry said: “Antidepressants are the second most prescribed drug in this country, and there are millions of implants placed every year around the world, so this applies everywhere, not just the U.S.”
Bearing this in mind, the researchers stress that communication between dentist and patient is of especial importance. Researcher and Clinical Assistant Professor Dr. Latifa Bairam said, “For patients who have been on antidepressants a long time, we’re not telling them to quit their medication. We just want them to be aware — the dentist, patient, and physician. It’s cooperation between all the parties to manage the procedure.”
“It would really be useful if patients provided the dentist with a current picture of lab tests, which would be helpful in treatment planning for the placement of the implant,” Dr. Bairam concluded.
Study: Antidepressants linked to dental implant failure [via Dr.Bicuspid]